Born in Milan, after graduating from the Conservatorio G. Verdi in double bass and percussions, at the age of 22 he entered the Teatro alla Scala orchestra, where he played with the most prestigious conductors. This inspiring confrontation with the greatest conductors prompted him to return to the Conservatory, where he graduated in composition and conducting.

Daniele Callegari from 1998 to 2001 was Principal Conductor at the Wexford Opera Festival. From 2002 to 2008 he was Chief Conductor of De Filharmonie (Royal Flanders Philharmonic Orchestra) of Antwerpen.

Daniele Callegari has conducted some of the major symphonic orchestras in the world, such as: Orchestre Metropolitain de Montréal, Orchestre National de l'Île de France, Belgian National Orchestra, Orchestre philharmonique de Monte-Carlo, La Monnaie Symphony Orchestra, Rotterdam Philharmonic Orchestra, Orchestre National de France, Orchestra Sinfonica Nazionale della RAI, Orchestra dell’Accademia Nazionale di Santa Cecilia, Münchner Rundfunkorchester, Tokyo Philharmonic Orchestra, Spanish National Orchestra, Orchestra Sinfonica di Milano Giuseppe Verdi.

He is regular guest at national and international leading concert halls and opera houses, including Metropolitan Opera in New York, Carnegie Hall in New York, Teatro alla Scala, Teatro La Fenice in Venice, Opéra National de Paris, Théâtre des Champs-Elysées, Liceu de Barcelona, Wiener Staatsoper, Staatsoper Berlin, Bayerische Staatsoper Munich, Staatsoper Hamburg, Semperoper Dresden, Staatstheater Stuttgart, Festival Verdi in Parma, Opéra du Rhin de Strasbourg, Opéra de Monte-Carlo, Grand Théatre de Genève, Den Norske Opera in Oslo, Washington Opera, San Francisco Opera, San Diego Opera, Opéra de Montréal, New National Theatre Tokyo, NCPA of Beijing, Arts Center Seoul, New Israeli Opera Tel Aviv.